Risk factors for and prediction of mortality in critically ill medical-surgical patients receiving heparin thromboprophylaxis.

ABSTRACT:

Background

Previous studies have suggested that prediction models for mortality should be adjusted for additional risk factors beyond the Acute Physiology and Chronic Health Evaluation (APACHE) score. Our objective was to identify risk factors independent of APACHE II score and construct a prediction model to improve the predictive accuracy for hospital and intensive care unit (ICU) mortality.

Methods

We used data from a multicenter randomized controlled trial (PROTECT, Prophylaxis for Thromboembolism in Critical Care Trial) to build a new prediction model for hospital and ICU mortality. Our primary outcome was all-cause 60-day hospital mortality, and the secondary outcome was all-cause 60-day ICU mortality.

Results

We included 3746 critically ill non-trauma medical-s

SUBMITTER: Li G 

PROVIDER: S-EPMC4769241 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature