Plasma pro-atrial natriuretic peptide to indicate fluid balance during cystectomy: a prospective observational study.

ABSTRACT:

Objectives

During surgery the volume of administered fluid is debated. Pro-atrial natriuretic peptide (proANP) is released by atrial distension, and we evaluated the relationship between changes in proANP associated with perioperative fluid balance.

Design

Prospective observational study.

Setting

One university/tertiary centre.

Participants

The study included patients who underwent radical cystectomy. Plasma for determination of proANP was obtained before surgery, after resection of the bladder, and at the end of surgery for 20 robotic-assisted radical cystectomy (RARC) and 20 open radical cystectomy (ORC) procedures.

Results

The blood loss was 1871 (95% CI 1267 to 2475) vs 589 mL (378 to 801) in the ORC and RARC groups (p=0.001), respectively, and fluid

SUBMITTER: Rasmussen KC 

PROVIDER: S-EPMC4769390 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature