Gait phenotype from mild cognitive impairment to moderate dementia: results from the GOOD initiative.

ABSTRACT:

Background and purpose

The differences in gait abnormalities from the earliest to the later stages of dementia and in the different subtypes of dementia have not been fully examined. This study aims to compare spatiotemporal gait parameters in cognitively healthy individuals, patients with amnestic mild cognitive impairment (MCI) and non-amnestic MCI, and patients with mild and moderate stages of Alzheimer's disease (AD) and non-Alzheimer's disease (non-AD).

Methods

Based on a cross-sectional design, 1719 participants (77.4 ± 7.3 years, 53.9% female) were recruited from cohorts from seven countries participating in the Gait, Cognition and Decline (GOOD) initiative. Mean values and coefficients of variation of spatiotemporal gait parameters were measured during normal pace wa

SUBMITTER: Allali G 

PROVIDER: S-EPMC4769662 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature