Current and Future Considerations for the Treatment of Hospital-Acquired Pneumonia.

ABSTRACT:

Unlabelled

Hospital-acquired pneumonia (HAP) and health-care-associated pneumonia (HCAP) are leading causes of death, morbidity, and resource utilization in hospitalized patients, and are associated with a broad range of Gram-positive and Gram-negative pathogens. Here, we discuss the different definitions of HAP and HCAP, review current guidelines regarding the treatment of these conditions, highlight the shortcomings of current therapeutic options, and discuss new antibiotic treatments. To optimize therapeutic outcomes in patients with HAP/HCAP, initial antimicrobial treatment must be appropriate and should be given as soon as possible; inappropriate or delayed therapy greatly increases morbidity and mortality. Selection of the most appropriate antimicrobial agent depends on the c

SUBMITTER: Montravers P 

PROVIDER: S-EPMC4769724 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature