Patient considerations in type 2 diabetes - role of combination dapagliflozin-metformin XR.

ABSTRACT:

Purpose

The purpose of this review article is to provide guidance to health care providers regarding the use of dapagliflozin-metformin XR (extended release) as a therapeutic option for the treatment of patients with type 2 diabetes mellitus (T2DM).

Methods

The PubMed database was searched through August 2015 to identify clinical trials and meta-analyses evaluating the use of the sodium-glucose cotransporter type 2 inhibitor dapagliflozin administered as monotherapy or in combination with metformin.

Results

Fourteen studies were included for this review, six of which evaluated dapagliflozin in combination with metformin, one of which evaluated dapagliflozin monotherapy, and four of which evaluated dapagliflozin as an add-on therapy to other antidiabetic agents. The co

SUBMITTER: Kuecker CM 

PROVIDER: S-EPMC4770010 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature