Different systolic blood pressure targets for people with history of stroke or transient ischaemic attack: PAST-BP (Prevention After Stroke--Blood Pressure) randomised controlled trial.

ABSTRACT:

Objective

To assess whether using intensive blood pressure targets leads to lower blood pressure in a community population of people with prevalent cerebrovascular disease.

Design

Open label randomised controlled trial.

Setting

99 general practices in England, with participants recruited in 2009-11.

Participants

People with a history of stroke or transient ischaemic attack whose systolic blood pressure was 125 mm Hg or above.

Interventions

Intensive systolic blood pressure target (<130 mm Hg or 10 mm Hg reduction from baseline if this was <140 mm Hg) or standard target (<140 mm Hg). Apart from the different target, patients in both arms were actively managed in the same way with regular reviews by the primary care team.

Main outcome measure

Change

SUBMITTER: Mant J 

PROVIDER: S-EPMC4770816 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature