A Novel Analog Reasoning Paradigm: New Insights in Intellectually Disabled Patients.

ABSTRACT:

Background

Intellectual Disability (ID) is characterized by deficits in intellectual functions such as reasoning, problem-solving, planning, abstract thinking, judgment, and learning. As new avenues are emerging for treatment of genetically determined ID (such as Down's syndrome or Fragile X syndrome), it is necessary to identify objective reliable and sensitive outcome measures for use in clinical trials.

Objective

We developed a novel visual analogical reasoning paradigm, inspired by the Progressive Raven's Matrices, but appropriate for Intellectually Disabled patients. This new paradigm assesses reasoning and inhibition abilities in ID patients.

Methods

We performed behavioural analyses for this task (with a reaction time and error rate analysis, Study 1) in 96 hea

SUBMITTER: Curie A 

PROVIDER: S-EPMC4771701 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature