Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity.

ABSTRACT:

Background

Studies suggest that fish consumption can restrict weight gain. However, little is known about how fish consumption affects gestational weight gain (GWG), and whether this relationship depends on genetic makeup.

Objective

To examine the association between fish consumption and GWG, and whether this relationship is dependent on molecular genetic predisposition to obesity.

Design

A nested case-cohort study based on the Danish National Birth Cohort (DNBC) sampling the most obese women (n = 990) and a random sample of the remaining participants (n = 1,128). Replication of statistically significant findings was attempted in the Avon Longitudinal Study of Parents and Children (ALSPAC) (n = 4,841). We included 32 body mass index (BMI) associated single nucleotide

SUBMITTER: Larsen SC 

PROVIDER: S-EPMC4773113 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature