Observer variability of absolute and relative thrombus density measurements in patients with acute ischemic stroke.

ABSTRACT:

Introduction

Thrombus density may be a predictor for acute ischemic stroke treatment success. However, only limited data on observer variability for thrombus density measurements exist. This study assesses the variability and bias of four common thrombus density measurement methods by expert and non-expert observers.

Methods

For 132 consecutive patients with acute ischemic stroke, three experts and two trained observers determined thrombus density by placing three standardized regions of interest (ROIs) in the thrombus and corresponding contralateral arterial segment. Subsequently, absolute and relative thrombus densities were determined using either one or three ROIs. Intraclass correlation coefficient (ICC) was determined, and Bland-Altman analysis was performed to evaluat

SUBMITTER: Santos EM 

PROVIDER: S-EPMC4773501 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature