Electrical source imaging of interictal spikes using multiple sparse volumetric priors for presurgical epileptogenic focus localization.

ABSTRACT: Electrical source imaging of interictal spikes observed in EEG recordings of patients with refractory epilepsy provides useful information to localize the epileptogenic focus during the presurgical evaluation. However, the selection of the time points or time epochs of the spikes in order to estimate the origin of the activity remains a challenge. In this study, we consider a Bayesian EEG source imaging technique for distributed sources, i.e. the multiple volumetric sparse priors (MSVP) approach. The approach allows to estimate the time courses of the intensity of the sources corresponding with a specific time epoch of the spike. Based on presurgical averaged interictal spikes in six patients who were successfully treated with surgery, we estimated the time courses of the source intensitie

SUBMITTER: Strobbe G 

PROVIDER: S-EPMC4773507 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature