The fat mass- and obesity-associated locus and dietary intake in children.

ABSTRACT:

Background

A region of chromosome 16 containing the fat mass-and obesity-associated gene (FTO) is reproducibly associated with fat mass and body mass index (BMI), risk of obesity, and adiposity.

Objectives

We aimed to assess the possibility that appetite plays a role in the association between FTO and BMI.

Design

Detailed dietary report information from the Avon Longitudinal Study of Parents and Children allowed the exploration of relations between FTO variation and dietary intake. Analyses were performed to investigate possible associations between variation at the FTO locus and the intake of a range of micronutrients and macronutrients, with adjustment for the bias often found within dietary report data when factors related to BMI are assessed. To test the hypothesi

SUBMITTER: Timpson NJ 

PROVIDER: S-EPMC4773885 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature