Genetic Markers of the Host in Persons Living with HTLV-1, HIV and HCV Infections.

ABSTRACT: Human T-cell leukemia virus type 1 (HTLV-1), hepatitis C virus (HCV) and human immunodeficiency virus type 1 (HIV-1) are prevalent worldwide, and share similar means of transmission. These infections may influence each other in evolution and outcome, including cancer or immunodeficiency. Many studies have reported the influence of genetic markers on the host immune response against different persistent viral infections, such as HTLV-1 infection, pointing to the importance of the individual genetic background on their outcomes. However, despite recent advances on the knowledge of the pathogenesis of HTLV-1 infection, gaps in the understanding of the role of the individual genetic background on the progress to disease clinically manifested still remain. In this scenario, much less is known r

SUBMITTER: Assone T 

PROVIDER: S-EPMC4776193 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature