Cerebrolysin combined with rehabilitation promotes motor recovery in patients with severe motor impairment after stroke.

ABSTRACT:

Background

Cerebrolysin is a neuropeptide preparation with neuroprotective and neurorestorative effects. Combining Cerebrolysin treatment with a standardized rehabilitation program may have a potential synergistic effect in the subacute stage of stroke. This study aims to evaluate whether Cerebrolysin provides additional motor recovery on top of rehabilitation therapy in the subacute stroke patients with moderate to severe motor impairment.

Methods

This phase IV trial was designed as a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. A total of 70 patients (Cerebrolysin n = 35, placebo n = 35) with moderate to severe motor function impairment were included within 7 days after stroke onset and were randomized to receive a 21-day tr

SUBMITTER: Chang WH 

PROVIDER: S-EPMC4776414 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature