Visual Field Outcomes for the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT).

ABSTRACT:

Purpose

The Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) showed that acetazolamide provided a modest, significant improvement in mean deviation (MD). Here, we further analyze visual field changes over the 6-month study period.

Methods

Of 165 subjects with mild visual loss in the IIHTT, 125 had perimetry at baseline and 6 months. We evaluated pointwise linear regression of visual sensitivity versus time to classify test locations in the worst MD (study) eye as improving or not; pointwise changes from baseline to month 6 in decibels; and clinical consensus of change from baseline to 6 months.

Results

The average study eye had 36 of 52 test locations with improving sensitivity over 6 months using pointwise linear regression, but differences between the ac

SUBMITTER: Wall M 

PROVIDER: S-EPMC4777274 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature