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ABSTRACT: Background
Intravenous (IV) hydration is considered a protective factor in reducing the incidence of acyclovir-induced nephrotoxicity. A systems-based review of cases of acyclovir-associated acute kidney injury can be used to examine institution-, care provider-, and task-related factors involved in administering the drug and can serve as a basis for developing a quality improvement intervention to achieve safer administration of acyclovir.Objectives
To explore the effectiveness of the study institution's inter-disciplinary quality improvement intervention in increasing the dilution of acyclovir before IV administration.Methods
After conducting a systems-based review for intervention development, a retrospective analysis was undertaken to compare IV administration o
SUBMITTER: Dubrofsky L
PROVIDER: S-EPMC4777587 | biostudies-literature | 2016 Jan-Feb
REPOSITORIES: biostudies-literature