DAPHNE: A New Tool for the Assessment of the Behavioral Variant of Frontotemporal Dementia.

ABSTRACT:

Background

The diagnosis of behavioral variant of frontotemporal dementia (bvFTD) relies primarily on clinical features and remains challenging. The specificity of the recently revised criteria can be disappointing, justifying development of new clinical tools.

Objective

We produced a behavioral inventory named DAPHNE. This scale (adapted from Rascovsky's criteria) explores six domains: disinhibition, apathy, perseverations, hyperorality, personal neglect and loss of empathy. It is composed of ten items (five answer categories). The aim was (1) to assess the validity and reliability of DAPHNE and (2) to evaluate its contribution in differentiating patients.

Methods

Two scores were computed: DAPHNE-6 (screening) from the six domains and DAPHNE-40 (diagnosis) from the t

SUBMITTER: Boutoleau-Bretonniere C 

PROVIDER: S-EPMC4777961 | biostudies-literature | 2015 Sep-Dec

REPOSITORIES: biostudies-literature