Asymmetric α-amination of β-keto esters using a guanidine-bisurea bifunctional organocatalyst.

ABSTRACT: An asymmetric α-amination of β-keto esters with azodicarboxylate in the presence of a guanidine-bisurea bifunctional organocatalyst was investigated. The α-amination products were obtained in up to 99% yield with up to 94% ee.

SUBMITTER: Odagi M 

PROVIDER: S-EPMC4778535 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature