Ontology highlight
ABSTRACT:
SUBMITTER: Bouhifd M
PROVIDER: S-EPMC4778566 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
ALTEX 20150304 2
The Human Toxome Project, funded as an NIH Transformative Research grant 2011-2016, is focused on developing the concepts and the means for deducing, validating and sharing molecular pathways of toxicity (PoT). Using the test case of estrogenic endocrine disruption, the responses of MCF-7 human breast cancer cells are being phenotyped by transcriptomics and mass-spectroscopy-based metabolomics. The bioinformatics tools for PoT deduction represent a core deliverable. A number of challenges for qu ...[more]