Transcriptome profiling of Musculus longissimus dorsi in two cattle breeds with different intramuscular fat deposition.

ABSTRACT: Intramuscular fat (IMF) deposition is a physiological process in cattle and is highly variable among breeds suggesting a large influence of genetic factors besides environmental factors. In order to elucidate molecular pathways underlying the genetic variation in this trait we compared transcriptomes of Musculus longissimus dorsi (MLD) in steers of Japanese Black and Holstein Friesian cattle breeds fed a high energy diet typically applied in Japan to achieve maximum IMF content. We identified a total of 569 differentially expressed genes (DEGs) with the majority (433) up-regulated in Japanese Black cattle. This breed is characterized by an extreme capacity for IMF deposition. Subsequent Ingenuity Pathway Analysis (IPA) revealed a gene network linking parameters of cell morphology and maint

SUBMITTER: Albrecht E 

PROVIDER: S-EPMC4778623 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature