Menses resumption after cancer treatment-induced amenorrhea occurs early or not at all.

ABSTRACT:

Objective

To identify factors associated with cancer treatment-induced amenorrhea and time to return of menses.

Design

Population-based cohort study.

Setting

Not applicable.

Patient(s)

Female cancer survivors who were diagnosed with cancer between the ages of 20 and 35 and were at least 2 years postdiagnosis at the time of recruitment (median = 7 years; interquartile range, 5-11).

Intervention(s)

None.

Main outcome measure(s)

Amenorrhea (≥6 months without menses) and resumption of menses.

Result(s)

After excluding women with hysterectomies before cancer diagnosis, 1,043 women were eligible for analysis. Amenorrhea occurred in 31.6% of women. Among women treated with chemotherapy (n = 596), older age at diagnosis (30-35 vs. 20-24 years: adju

SUBMITTER: Jacobson MH 

PROVIDER: S-EPMC4779728 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature