Use of Guideline-Directed Medications for Heart Failure Before Cardioverter-Defibrillator Implantation.

ABSTRACT:

Background

Guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) is recommended before primary prevention implantable cardioverter-defibrillator (ICD) placement. Adherence to this recommendation and associated outcomes are unknown.

Objectives

This study examined the use of GDMT (≥1 prescription filled for both a renin-angiotensin inhibitor [RAI] and a heart failure-approved beta-blocker [HFBB]) within 90 days before primary prevention ICD placement in patients with HFrEF.

Methods

Data from the National Cardiovascular Data Registry ICD Registry were merged with a 40% random sample of Medicare administrative data. Prescription fills for recipients of primary prevention ICD between 2007 and 2011 were examined, analyzing GDMT o

SUBMITTER: Roth GA 

PROVIDER: S-EPMC4780248 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature