A comparative study between limb-salvage and amputation for treating osteosarcoma.

ABSTRACT:

Purpose

Osteosarcoma is an aggressive malignant neoplasm, and conflicting findings have been reported on the survival and function recovery in osteosarcoma patients experiencing limb salvage or amputation. In the present study, we compared clinical outcomes regarding limb salvage surgery vs. amputation for osteosarcoma patients by a meta-analysis.

Method

Literature search was conducted in CNKI, Medline, Embase, the Cochrane Database, and Web of Sciences, and the quality of included studies was evaluated based on Newcastle-Ottawa scale quality assessment. Odds ratio and 95% confidence interval of the local recurrence, 5-year overall survival, and metastasis occurrence were calculated.

Results

17 articles were included according to selection criteria. There were 1343 pa

SUBMITTER: Li X 

PROVIDER: S-EPMC4782023 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature