Antiepileptic use for epilepsy and nonepilepsy disorders: A population-based study (1998-2013).

ABSTRACT:

Objective

To examine the trends in antiepileptic drug (AED) use among individuals living in Manitoba with and without a history of epilepsy.

Methods

Using data obtained from administrative health databases in Manitoba, we assessed the quarterly prevalence of AED use between 1998 and 2013 among individuals with and without a history of epilepsy using cross-sectional time series analysis.

Results

Over the study period, the number of individuals prescribed AEDs increased more than 3-fold, from 8,883 to 27,246. The prevalence of AED use among patients with epilepsy increased by 3%, from 789.6 per 1,000 in 1998/1999 to 813.9 per 1,000 in 2012/2013 (p < 0.001 after 2006). In contrast, we observed a 210% increase in AED use among patients without epilepsy from 6.8 to 21.1 pe

SUBMITTER: Leong C 

PROVIDER: S-EPMC4782115 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature