Single-subject morphological brain networks: connectivity mapping, topological characterization and test-retest reliability.

ABSTRACT:

Introduction

Structural MRI has long been used to characterize local morphological features of the human brain. Coordination patterns of the local morphological features among regions, however, are not well understood. Here, we constructed individual-level morphological brain networks and systematically examined their topological organization and long-term test-retest reliability under different analytical schemes of spatial smoothing, brain parcellation, and network type.

Methods

This study included 57 healthy participants and all participants completed two MRI scan sessions. Individual morphological brain networks were constructed by estimating interregional similarity in the distribution of regional gray matter volume in terms of the Kullback-Leibler divergence measure. G

SUBMITTER: Wang H 

PROVIDER: S-EPMC4782249 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature