Association of ACE Gene I/D polymorphism with migraine in Kashmiri population.

ABSTRACT:

Introduction

Migraine is a complex, recurrent headache disorder that is one of the most common complaints in neurology practice. The role of various genes in its pathogenesis is being studied. We did this study to see whether an association exists between ACE gene I/D polymorphism and migraine in our region.

Materials and methods

The study included 100 patients diagnosed with migraine and 121 healthy controls. The study subject were age and gender matched. The analysis was based on Polymerase Chain Reaction (PCR) and included following steps: DNA extraction from blood, PCR and Restriction Fragment Length Polymorphism (RFLP).

Results

Out of 100 cases, 69 were females and 31 were males. Fifty-seven were having migraine without aura and 43 had migraine with aura. 45 of t

SUBMITTER: Wani IY 

PROVIDER: S-EPMC4782560 | biostudies-literature | 2016 Jan-Mar

REPOSITORIES: biostudies-literature