Lymphatic transport in patients with chronic venous insufficiency and venous leg ulcers following sequential pneumatic compression.

ABSTRACT:

Background

Recent advancements in near-infrared fluorescence lymphatic imaging (NIRFLI) technology provide opportunities for non-invasive, real-time assessment of lymphatic contribution in the etiology and treatment of ulcers. The objective of this study was to assess lymphatics in subjects with venous leg ulcers using NIRFLI and to assess lymphatic impact of a single session of sequential pneumatic compression (SPC).

Methods

Following intradermal microdoses of indocyanine green (ICG) as a lymphatic contrast agent, NIRFLI was used in a pilot study to image the lymphatics of 12 subjects with active venous leg ulcers (Clinical, Etiologic, Anatomic, and Pathophysiologic [CEAP] C6). The lymphatics were imaged before and after a single session of SPC to assess impact on lymphatic

SUBMITTER: Rasmussen JC 

PROVIDER: S-EPMC4782606 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature