Contextual Modulation of Vocal Behavior in Mouse: Newly Identified 12 kHz "Mid-Frequency" Vocalization Emitted during Restraint.

ABSTRACT: While several studies have investigated mouse ultrasonic vocalizations (USVs) emitted by isolated pups or by males in mating contexts, studies of behavioral contexts other than mating and vocalization categories other than USVs have been limited. By improving our understanding of the vocalizations emitted by mice across behavioral contexts, we will better understand the natural vocal behavior of mice and better interpret vocalizations from mouse models of disease. Hypothesizing that mouse vocal behavior would differ depending on behavioral context, we recorded vocalizations from male CBA/CaJ mice across three behavioral contexts including mating, isolation, and restraint. We found that brief restraint elevated blood corticosterone levels of mice, indicating increased stress relative to iso

SUBMITTER: Grimsley JM 

PROVIDER: S-EPMC4783392 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature