Lessons learned: Infrastructure development and financial management for large, publicly funded, international trials.

ABSTRACT:

Background/aims

Randomized clinical trials are widely recognized as essential to address worldwide clinical and public health research questions. However, their size and duration can overwhelm available public and private resources. To remain competitive in international research settings, advocates and practitioners of clinical trials must implement practices that reduce their cost. We identify approaches and practices for large, publicly funded, international trials that reduce cost without compromising data integrity and recommend an approach to cost reporting that permits comparison of clinical trials.

Methods

We describe the organizational and financial characteristics of The International Network for Strategic Initiatives in Global HIV Trials, an infectious disease res

SUBMITTER: Larson GS 

PROVIDER: S-EPMC4785062 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature