CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid.

ABSTRACT: An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii-derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.

SUBMITTER: Miriagou V 

PROVIDER: S-EPMC478546 | biostudies-literature | 2004 Aug

REPOSITORIES: biostudies-literature