Less invasive beractant administration in preterm infants: a pilot study.

ABSTRACT:

Objectives

The aims of this study were to assess the efficacy and feasibility of a new, less invasive surfactant administration technique for beractant replacement using a specifically designed cannula in preterm infants born at <32 weeks of gestation and to compare short- and long-term outcomes between this approach and standard treatment, consisting of intubation, administration of surfactant and early extubation to nasal continuous positive airway pressure.

Method

This was a single-center, prospective, open-label, non-randomized, controlled pilot study with an experimental cohort of 30 patients treated with less invasive surfactant administration and a retrospective control group comprising the 30 patients most recently treated with the standard approach. Beractant (4 ml/

SUBMITTER: Ramos-Navarro C 

PROVIDER: S-EPMC4785853 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature