Viruses as Sole Causative Agents of Severe Acute Respiratory Tract Infections in Children.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) and influenza A viruses are known to cause severe acute respiratory tract infections (SARIs) in children. For other viruses like human rhinoviruses (HRVs) this is less well established. Viral or bacterial co-infections are often considered essential for severe manifestations of these virus infections.

Objective

The study aims at identifying viruses that may cause SARI in children in the absence of viral and bacterial co-infections, at identifying disease characteristics associated with these single virus infections, and at identifying a possible correlation between viral loads and disease severities.

Study design

Between April 2007 and March 2012, we identified children (<18 year) with or without a medical history, admitted

SUBMITTER: Moesker FM 

PROVIDER: S-EPMC4786225 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature