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Data for stable formulation of steroid hormone receptor-targeted liposomes for cancer therapeutics.

ABSTRACT: A detailed description of steroid hormone ligand containing liposomes and their stability has been given. Liposomes were complexed with ?-gal DNA and used to transfect cancer and non-cancer cells. The stability of the liposomes and lipoplexes were analysed using dynamic light scattering and DNA-binding gel images. The formulations were used to assess the delivery of anticancer gene, p53 in cancer cells. The dataset consists of DNA-binding gel images, transfection, cytotoxicity and reverse transcriptase PCR images.

SUBMITTER: Sharma P 

PROVIDER: S-EPMC4786751 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Data for stable formulation of steroid hormone receptor-targeted liposomes for cancer therapeutics.

Sharma Priyanka P   Banerjee Rajkumar R   Narayan Kumar Pranav KP  

Data in brief 20160227

A detailed description of steroid hormone ligand containing liposomes and their stability has been given. Liposomes were complexed with β-gal DNA and used to transfect cancer and non-cancer cells. The stability of the liposomes and lipoplexes were analysed using dynamic light scattering and DNA-binding gel images. The formulations were used to assess the delivery of anticancer gene, p53 in cancer cells. The dataset consists of DNA-binding gel images, transfection, cytotoxicity and reverse transc  ...[more]

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