Brain response to viewing others being harmed in children with conduct disorder symptoms.

ABSTRACT:

Background

Deficient empathic processing is thought to foster conduct disorder (CD). It is important to determine the extent to which neural response associated with perceiving harm to others predicts CD symptoms and callous disregard for others.

Methods

A total of 107 9- to 11-year-old children (52 female) were recruited from pediatric and mental health clinics, representing a wide range of CD symptoms. Children were scanned with functional magnetic resonance imaging while viewing brief video clips of persons being harmed intentionally or accidentally.

Results

Perceiving harm evoked increased hemodynamic response in the anterior insula (aINS), anterior cingulate cortex (ACC), amygdala, periaqueductal gray (PAG), caudate, and inferior parietal lobe (IPL) across all pa

SUBMITTER: Michalska KJ 

PROVIDER: S-EPMC4789171 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature