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Perioperative treatment options in resectable pancreatic cancer - how to improve long-term survival.


ABSTRACT: Surgery remains the only chance of cure for pancreatic cancer, but only 15%-25% of patients present with resectable disease at the time of primary diagnosis. Important goals in clinical research must therefore be to allow early detection with suitable diagnostic procedures, to further broaden operation techniques and to determine the most effective perioperative treatment of either chemotherapy and/or radiation therapy. More extensive operations involving extended pancreatectomy, portal vein resection and pancreatic resection in resectable pancreatic cancer with limited liver metastasis, performed in specialized centers seem to be the surgical procedures with a possible impact on survival. After many years of stagnation in pharmacological clinical research on advanced pancreatic ductal ade

SUBMITTER: Sinn M 

PROVIDER: S-EPMC4789610 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature