Neuroanatomical anomalies of dyslexia: Disambiguating the effects of disorder, performance, and maturation.

ABSTRACT: An increasing body of studies has revealed neuroanatomical impairments in developmental dyslexia. However, whether these structural anomalies are driven by dyslexia (disorder-specific effects), absolute reading performance (performance-dependent effects), and/or further influenced by age (maturation-sensitive effects) remains elusive. To help disentangle these sources, the current study used a novel disorder (dyslexia vs. control) by maturation (younger vs. older) factorial design in 48 Chinese children who were carefully matched. This design not only allows for direct comparison between dyslexics versus controls matched for chronological age and reading ability, but also enables examination of the influence of maturation and its interaction with dyslexia. Voxel-based morphometry (VBM) sho

SUBMITTER: Xia Z 

PROVIDER: S-EPMC4790432 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature