Characterization of the temporo-parietal junction by combining data-driven parcellation, complementary connectivity analyses, and functional decoding.

ABSTRACT: The right temporo-parietal junction (RTPJ) is consistently implicated in two cognitive domains, attention and social cognitions. We conducted multi-modal connectivity-based parcellation to investigate potentially separate functional modules within RTPJ implementing this cognitive dualism. Both task-constrained meta-analytic coactivation mapping and task-free resting-state connectivity analysis independently identified two distinct clusters within RTPJ, subsequently characterized by network mapping and functional forward/reverse inference. Coactivation mapping and resting-state correlations revealed that the anterior cluster increased neural activity concomitantly with a midcingulate-motor-insular network, functionally associated with attention, and decreased neural activity concomitantly w

SUBMITTER: Bzdok D 

PROVIDER: S-EPMC4791053 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature