Premature Birth and Large for Gestational Age Are Associated with Risk of Barrett's Esophagus in Adults.

ABSTRACT:

Background

Birth characteristics, including weight and gestational age, may be associated with risk of Barrett's esophagus (BE), the only known precursor for esophageal adenocarcinoma; however, data are limited.

Aims

To examine associations between various birth characteristics and BE, and whether these associations are mediated by known risk factors for BE.

Methods

Data were obtained from a cross-sectional study among eligible Veterans Affairs patients scheduled for an upper endoscopy, and a sample identified from primary care clinics. Participants underwent an esophagogastroduodenoscopy and completed a survey that captured information on sociodemographic and clinical factors, as well as birth information. We compared 263 patients with histologically confirmed BE to

SUBMITTER: Shiota S 

PROVIDER: S-EPMC4791183 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature