Regional Patterns of Elevated Alpha and High-Frequency Electroencephalographic Activity during Nonrapid Eye Movement Sleep in Chronic Insomnia: A Pilot Study.

ABSTRACT:

Study objectives

To examine nonrapid eye movement (NREM) sleep in insomnia using high-density electroencephalography (EEG).

Methods

All-night sleep recordings with 256 channel high-density EEG were analyzed for 8 insomnia subjects (5 females) and 8 sex and age-matched controls without sleep complaints. Spectral analyses were conducted using unpaired t-tests and topographical differences between groups were assessed using statistical non-parametric mapping. Five minute segments of deep NREM sleep were further analyzed using sLORETA cortical source imaging.

Results

The initial topographic analysis of all-night NREM sleep EEG revealed that insomnia subjects had more high-frequency EEG activity (> 16 Hz) compared to good sleeping controls and that the difference between g

SUBMITTER: Riedner BA 

PROVIDER: S-EPMC4791614 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature