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Exercise training in patients with heart failure and preserved ejection fraction: meta-analysis of randomized control trials.


ABSTRACT:

Background

Heart failure with preserved ejection fraction (HFPEF) is common and characterized by exercise intolerance and lack of proven effective therapies. Exercise training has been shown to be effective in improving cardiorespiratory fitness (CRF) in patients with systolic heart failure. In this meta-analysis, we aim to evaluate the effects of exercise training on CRF, quality of life, and diastolic function in patients with HFPEF.

Methods and results

Randomized controlled clinical trials that evaluated the efficacy of exercise training in patients with HFPEF were included in this meta-analysis. Primary outcome of the study was change in CRF (measured as change in peak oxygen uptake). Effect of exercise training on quality of life (estimated using Minnesota living with h

SUBMITTER: Pandey A 

PROVIDER: S-EPMC4792111 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature