Phoxilium(®) reduces hypophosphataemia and magnesium supplementation during continuous renal replacement therapy.

ABSTRACT:

Background

Although associated with severe clinical complications, phosphate remains a neglected ion. Additionally, phosphate balance during continuous renal replacement therapy (CRRT) is complex and multifunctional. The present retrospective study investigated the effects of phosphate-containing CRRT fluid on phosphate homeostasis.

Methods

We retrospectively analysed 112 patients treated with CRRT at Skåne University Hospital, Sweden. The control group was treated with Hemosol(®) B0 (no phosphate; n = 36) as dialysis and replacement fluid, while the study group received Phoxilium(®) (phosphate; n = 76) as dialysis fluid and Hemosol(®) B0 as replacement fluid.

Results

Hypophosphataemia (<0.7 mM) occurred in 15% of the treatment days in the control group compared with

SUBMITTER: Godaly G 

PROVIDER: S-EPMC4792612 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature