Early changes in body weight and blood pressure are associated with mortality in incident dialysis patients.

ABSTRACT:

Background

While much research is devoted to identifying novel biomarkers, addressing the prognostic value of routinely measured clinical parameters is of great interest. We studied early blood pressure (BP) and body weight (BW) trajectories in incident haemodialysis patients and their association with all-cause mortality.

Methods

In a cohort of 357 incident patients, we obtained all records of BP and BW during the first 90 days on dialysis (over 12 800 observations) and analysed trajectories using penalized B-splines and mixed linear regression models. Baseline comorbidities and all-cause mortality (median follow-up: 2.2 years) were obtained from the French Renal Epidemiology and Information Network (REIN) registry, and the association with mortality was assessed by Cox mod

SUBMITTER: Duranton F 

PROVIDER: S-EPMC4792627 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature