Risk of mortality and physiologic injury evident with lower alcohol exposure among HIV infected compared with uninfected men.

ABSTRACT:

Background

HIV infected (HIV+) individuals may be more susceptible to alcohol-related harm than uninfected individuals.

Methods

We analyzed data on HIV+ and uninfected individuals in the Veterans Aging Cohort Study (VACS) with an Alcohol Use Disorders Identification Test-Consumption AUDIT-C score from 2008 to 2012. We used Cox proportional hazards models to examine the association between alcohol exposure and mortality through July, 2014; and linear regression models to assess the association between alcohol exposure and physiologic injury based on VACS Index Scores. Models were adjusted for age, race/ethnicity, smoking, and hepatitis C infection.

Results

The sample included 18,145 HIV+ and 42,228 uninfected individuals. Among HIV+ individuals, 76% had undetectable HI

SUBMITTER: Justice AC 

PROVIDER: S-EPMC4792710 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature