Genetic polymorphisms of interleukin genes and the risk of Alzheimer's disease: An update meta-analysis.

ABSTRACT:

Objectives

Recently, several meta-analyses have reported an association between interleukin (IL) gene polymorphisms and the risk of Alzheimer's disease (AD). Several further papers discussing the relationship with the risk of AD have recently been published. The aim of this meta-analysis was to re-evaluate and update the associations between IL gene polymorphisms and the risk of AD.

Methods

The search sources were PubMed, Science Direct, Scopus, and Google Scholar up to July 2015, and the following search terms were used: "interleukin 1 or interleukin 6 or interleukin 10" and "variant or polymorphism or SNP" in combination with "Alzheimer's disease". A meta-analysis using the pooled odds ratios and 95% confidence intervals was carried out to assess the associations between f

SUBMITTER: Mun MJ 

PROVIDER: S-EPMC4792847 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature