Transcriptome analysis of different developmental stages of amphioxus reveals dynamic changes of distinct classes of genes during development.

ABSTRACT: Vertebrates diverged from other chordates approximately 500 million years ago and have adopted several modifications of developmental processes. Amphioxus is widely used in evolutionary developmental biology research, such as on the basic patterning mechanisms involved in the chordate body plan and the origin of vertebrates. The fast development of next-generation sequencing has advanced knowledge of the genomic organization of amphioxus; however, many aspects of gene regulation during amphioxus development have not been fully characterized. In this study, we applied high-throughput sequencing on the transcriptomes of 13 developmental stages of Chinese amphioxus to gain a comprehensive understanding of transcriptional processes occurring from the fertilized egg to the adult stage. The expr

SUBMITTER: Yang KY 

PROVIDER: S-EPMC4793263 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature