Dynamic gene expression profiles during postnatal development of porcine subcutaneous adipose.

ABSTRACT: A better understanding of the control of lipogenesis is of critical importance for both human and animal physiology. This requires a better knowledge of the changes of gene expression during the process of adipose tissue development. Thus, the objective of the current study was to determine the effects of development on subcutaneous adipose tissue gene expression in growing and adult pigs. Here, we present a comprehensive investigation of mRNA transcriptomes in porcine subcutaneous adipose tissue across four developmental stages using digital gene expression profiling. We identified 3,274 differential expressed genes associated with oxidative stress, immune processes, apoptosis, energy metabolism, insulin stimulus, cell cycle, angiogenesis and translation. A set of universally abundant gen

SUBMITTER: Zhang J 

PROVIDER: S-EPMC4793310 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature