High-performance integrated virtual environment (HIVE): a robust infrastructure for next-generation sequence data analysis.

ABSTRACT: The High-performance Integrated Virtual Environment (HIVE) is a distributed storage and compute environment designed primarily to handle next-generation sequencing (NGS) data. This multicomponent cloud infrastructure provides secure web access for authorized users to deposit, retrieve, annotate and compute on NGS data, and to analyse the outcomes using web interface visual environments appropriately built in collaboration with research and regulatory scientists and other end users. Unlike many massively parallel computing environments, HIVE uses a cloud control server which virtualizes services, not processes. It is both very robust and flexible due to the abstraction layer introduced between computational requests and operating system processes. The novel paradigm of moving computations t

SUBMITTER: Simonyan V 

PROVIDER: S-EPMC4795927 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature