Paralimbic and lateral prefrontal encoding of reward value during intertemporal choice in attempted suicide.

ABSTRACT:

Background

Alongside impulsive suicide attempts, clinicians encounter highly premeditated suicidal acts, particularly in older adults. We have previously found that in contrast to the more impulsive suicide attempters' inability to delay gratification, serious and highly planned suicide attempts were associated with greater willingness to wait for larger rewards. This study examined neural underpinnings of intertemporal preference in suicide attempters. We expected that impulsivity and suicide attempts, particularly poorly planned ones, would predict altered paralimbic subjective value representations. We also examined lateral prefrontal and paralimbic correlates of premeditation in suicidal behavior.

Method

A total of 48 participants aged 46-90 years underwent extensive cli

SUBMITTER: Vanyukov PM 

PROVIDER: S-EPMC4797639 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature