A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides.

ABSTRACT: Sodium azide is toxic and widely used in agricultural, commercial products, and research laboratories. Thus it is of a significant environmental concern and there is a need for the development of a rapid detection method. A fluorogenic dibenzylcyclooctyne derivative (Fl-DIBO) is herein described as a fluorescent probe for the rapid detection of inorganic azide via Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC). Fl-DIBO was found to be highly selective toward NaN3 in comparison to other common anions with good sensitivity and detection limit of 10μM.

SUBMITTER: Wang K 

PROVIDER: S-EPMC4797929 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature