The Impact of Liver Cell Injury on Health-Related Quality of Life in Patients with Chronic Liver Disease.

ABSTRACT:

Background

Patients with chronic liver disease often suffer from unspecific symptoms and report severe impairment in the quality of life. The underlying mechanisms are multifactorial and include disease-specific but also liver related causes. The current analysis evaluated the association of hepatocellular apoptosis in non-viral chronic liver disease and health-related quality of life (HRQL). Furthermore we examined factors, which influence patient's physical and mental well-being.

Methods

A total of 150 patients with non-infectious chronic liver disease were included between January 2014 and June 2015. The German version of the Chronic Liver Disease Questionnaire (CLDQ-D), a liver disease specific instrument to assess HRQL, was employed. Hepatocellular apoptosis was determi

SUBMITTER: Alt Y 

PROVIDER: S-EPMC4798400 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature