Characterisation of the epidemic strain of H3N8 equine influenza virus responsible for outbreaks in South America in 2012.

ABSTRACT:

Background

An extensive outbreak of equine influenza occurred across multiple countries in South America during 2012. The epidemic was first reported in Chile then spread to Brazil, Uruguay and Argentina, where both vaccinated and unvaccinated animals were affected. In Brazil, infections were widespread within 3months of the first reported cases. Affected horses included animals vaccinated with outdated vaccine antigens, but also with the OIE-recommended Florida clade 1 strain South Africa/4/03.

Methods

Equine influenza virus strains from infected horses were isolated in eggs, then a representative strain was subjected to full genome sequencing using segment-specific primers with M13 tags. Phylogenetic analyses of nucleotide sequences were completed using PhyML. Amino acid s

SUBMITTER: Alves Beuttemmuller E 

PROVIDER: S-EPMC4799594 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature